6 min read

BiQ: Recap for the Week Ending April 4, 2025 (Premium)

Welcome to the BiQ Weekly Recap #11!

I want to welcome the new Biotech iQ members who joined this past week--thank you for joining the BiQ Community. I've been a biotech investor for over two decades, but BiQ is a new service, and I'm humbled and grateful for its warm reception from the biotech community.

If you haven't already done so, I encourage members to join the BiQ Community Chat Server on Discord.

Even if you don't have time to participate regularly, BiQ Chat is still the quickest way to receive updates, trade alerts (Premium only), and answers to questions.

Premium members have access to the Public and Premium channels, while Public members can access the Public channels. Click here for instructions on how to access the BiQ Community Chat Server.

While I do publish several articles and updates each week, please remember that Biotech iQ is much more than a newsletter service. BiQ's most valuable tools are found on the Biotech iQ website (www.biotechiq.com). These include:

  • The Active Portfolio displays a list of all companies currently included in Active Coverage, together with their outlook and ratings. These are updated at least once a week.
  • The Catalyst Tracker & Events Calendar displays a quarter-by-quarter list of upcoming catalysts and a calendar of forthcoming events.
  • The News Feed displays an RSS feed of all press releases from companies covered at Biotech iQ (if the company provides RSS services).
  • BiQ Community Chat

The XBI closed last Friday at 84.40, opened Monday at 81.59, and closed Friday at 73.64–falling almost 13% since last Friday's close. It reached an intra-week high of 81.66 and a low of 73.27. Over the past two weeks, since it opened at 87.78 on Monday, March 24th, the index has lost over 16% of its value.

XBI 1-Week Chart. Click image to enlarge.

Zooming out to the one-month chart, we can see the index has broken all near-term support levels.

XBI 1-Month Chart. Click image to enlarge.

Zooming further out to the one-year chart, we can put into perspective the amount of damage that has been done over the past week. One thing to note, however, is that the RSI is now showing very oversold conditions. According to the longer-term chart (not shown), the next significant long-term support level can be found in the 60-65 range, though there is also some evidence of support in the 72-73 range. However, while we can prognosticate all we want, the truth is that only time will tell what happens from here.

XBI 1-Year Chart. Click image to enlarge.

Biotech investors had to contend with two major disruptive events this past week. First was the forced resignation of Dr. Peter Marks from the FDA, which I briefly wrote about in my BiQ Portfolio Review article published earlier this week (link below). The second was the announcement of the very extreme set of tariffs imposed by President Trump against US trading partners. I will refrain from talking about the logic, or lack thereof, of the proposed tariffs because that's outside the scope of what I cover at Biotech iQ.

However, I would say that the current selloff in the XBI doesn't seem to be driven by any specific fundamental causes. There is (or at least there was) no financial crisis, no pandemic, and no other significant macro black-swan event–except for recent policy-driven events. However, it's challenging for me to view policy-driven changes as true black swan events, as they were intentionally contemplated, purposeful, and, from my viewpoint, almost seemed designed to create maximum disruption and confusion. Jmtc.

So, what happens from here? I wish I could say, but I have no crystal ball. Until leaders at the FDA and the White House provide some information to help calm investors' frazzled nerves, it is tough to predict which way the market will go from here. In my opinion, the best course of action seems to be to hope for the best but prepare for the worst. This means remaining rational, investing cautiously, and maintaining adequate liquidity. Retail investors are small fish in an ocean dominated by much larger fish with much bigger teeth. When the larger fish decide it's feeding time, sometimes it's safer just to find a reef to hide in until the waters are safe again.